Enterovirus 71 IgM Test Kits
EV71 IgM Dot Assay and Dot-ELISA kits can used in the field as Point-of-Care Test (POCT) device; EV71 IgM ELISA kit is suitable to screen large quantity of blood specimens.
EV71 Test Kits
EV-71 IgM DOT ELISA, EV-71 IgM ELISA and EV-71 IgM Dot Filtration Test Kits are a series of immunoassay test kits used for the qualitative detection of the IgM class antibodies to human enterovirus-71 (EV71) in serum or plasma samples, and are used in clinical laboratories for early diagnosis and management of patients infected with EV71, a.k.a. the 'hand-foot-mouth disease (HFMD)'.
The EV71 Dot Assay and Dot-ELISA kits are easy to perform, and no other reagent or equipment is needed, so they can used in the field as Point-of-Care Test (POCT) device; while EV71 IgM ELISA kit is suitable to screen large quantity of blood specimens, especially when the HFMD is epidemic in a region.
Second antibodies specific to human immunoglobulin M proteins (anti-µ chain) are pre-coated on the micro-well or nitrocellulose membrane as capturer; monoclonal anti-EV71 antibodies conjugated to the enzyme horseradish peroxidase (HRP-conjugate) or to colloidal gold as the color development indicator. If the tested target, EV71 IgM antibody present in the specimen, after the assay procedure, the second antibody-IgM antibody-antigen-HRP-conjugate (or colloidal gold) will accumulate in the test region. And color will be observed direct in the rapid test kit, or after certain color development procedure in the Dot-ELISA and ELISA method.
Enterovirus 71 and HFMD
Human Enterovirus 71 is one of the major causative agents for 'hand-foot-mouth disease (HFMD)', and is notable for its aetiological role in the epidemics of severe neurological diseases in children. The illness usually peaks in June or July. EV71 infection may be asymptomatic or may cause diarrhea and rashes.
Direct detection of virus is the mainstay of diagnosis of EV71 infection. EV 71 can be isolated from throat and stool specimens, as well as from skin vesicle fluid. Our EV71 specific serological assays can help in the diagnosis of the HFMD disease.