anti-ENA IgG Antibody Dot Filtration Assay Kit

ENA IgG Dot Assay Cassette

ENA IgG DOT Assay Kit is an in-vitro rapid test reagent kit for the qualitative detection of the IgG antibody specific to extractable Nuclear antigens (ENA) in human serum specimens. And this ENA IgG rapid test kit is intended to be used as an aid in the diagnosis and treatment of autoimmune connective tissue disorders.

ENA IgG Dot assay kit is designed to detect IgG class of antibodies to different ENA antigens in human serum specimens. On the test region of the nitrocellulose membrane is pre-coated with immobilized ENAs. During the test, the any of the antibodies specific to ENA will be captured and bound on the membrane. Then, the subsequently added goat anti-human IgG antibody conjugated with colloidal gold is added, it will be caught by the bound ENA antibodies, and a red dot will develop in the test region, indicating a positive result.

ENA Antibody and Rheumatoid Arthritis

Extractable Nuclear Antigens are soluble cytoplasmic and nuclear components. In recent years it has become clear that six autoantibodies to a number of nuclear constituents, namely Ro, La, Sm, RNP, Scl-70 and Jo1, have been proved to be useful in the diagnosis of various connective tissue diseases. Antibodies to these antigens have particular associations with various connective tissue disorders. For example, The Jo-1 autoantibody is specifically found in patients with myositis, and associated with a high incidence of accompanying interstitial lung disease. Antibodies to Sm marker are highly specific for patients with SLE and are considered a diagnostic criterion for SLE. So, the detection of these antibodies, particularly those of the IgG class, offers an efficient test method for the laboratory workup of patients with various connective tissue diseases.

anti-ENA IgG Antibody Dot Assay Kit

No.Cat. No.Description
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SpecimenPCS/BoxQuan. per CTN Quantity Interested* Add to
1 ENA R522 Extractable Nuclear IgG DOT Assay serum 25 Bulk: 1200 PCS
Boxed: 36 Boxes
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