MiA Urine Test
This Micro Albumin rapid test kit is used to qualitative detect micro albumin in human urine specimen, which is a prognostic indicator of kidney damage in its early stage.
Micro Albumin urine test kit is a chromatographic immunoassay for the semi-quantitative detection of micro-albumin in human urine specimen based on immuno competitive inhibition principle. The test result can be used in many clinical diagnostic situations, especially as a prognostic marker of kidney damages in its early stage.
Testing Principle of MiA Rapid Test
After added, the urine specimen will dissolve the pre-coated micro-albumin-specific monoclonal antibody labeled with colloidal gold. The micro-albumin, if present, will react with the conjugated antibody. If there is enough micro albumins in the urine, all the colloidal gold conjugated antibody will be bound, leaving no or very small amount of colloidal gold conjugated antibody to react with the micro albumin pre-coated in the test (T) region. So, no colloidal gold particle will be bound in the test region, thus no color develops in the test region, indicating a strong positive result (>50mg/L).
If the albumin concentration in the specimen is not high enough, and there are some colloidal gold conjugated antibody left to be bound in the test region, a dim pink line will develop in the test region, indicating the concentration is higher than normal value of 20mg/L, but lower than 50 mg/L. And, if test line is as dark as, or darker than, the reference line, it means the concentration is normal (<20 mg/L).
Micro-Albumin as Health Indicator
When the permeability for albumin in the renal glomerulus is abnormally high, micro-albumin in the blood will leak into the urine. Usually, the level of albumin produced by microalbuminuria is lower than that can be detected by our urine reagent strips. Usually, when the level is above 100 mg/L, it is considered serious microalbuminuria; when it is over 300 mg/L, it is then called macroalbuminuria or albuminuria.
The level of micro albumin can be used in many situations in clinical diagnosis realm, among them including: as an indicator of subclinical cardiovascular disease; as a marker of vascular endothelial dysfunction; as an important prognostic marker for kidney disease, such as diabetes mellitus and hypertension; and, as a risk factor for venous thromboembolism.